[Immunoglobulins in chronic tonsillitis].

Thirty patients aged 3-40 were tonsillectomized at the Clinic of Otorhinolaryngology in Novi Sad. The tonsils removed were fluoroscentically investigated to establish the presence of G, A and M immunoglobulins. The presence of all three immunoglobulin classes was confirmed in 60% of the investigated samples of tonsillar tissue. IgG producing plasma cells were seen in the largest number while IgA producing plasma cells were noticed in the least number. Immunoglobulins were positioned on the surface of the epithelium and in the subepithelial tissue. However, plasma cells were localized in interfollicular spaces in 85% of the cases which pointed to the existence of local immunoglobulin synthesis inasmuch as plasma cells were not found at all in 10% of the patients. Parallel pathohistologic and other investigations being now under way would give the basis for final opinion on local immunoglobulin synthesis and its part in chronic tonsillitis.