More Than Meets the Eye: Cerebrovascular Disease in Sickle Cell Disease Is About More Than Sickling.

A 56-year-old male with a known history of sickle cell disease (SCD) with HbSC and progressive deafness presented to the hospital with increased left-sided weakness accompanied by worsening confusion for the past 5 days. He experienced a multiorgan crisis requiring plasmapheresis 10 years prior. He had lived independently until moving in with his brother because of progressive cognitive problems. On presentation, he appeared mildly confused, with mild bilateral proximal weakness, and scored a 3 on the National Institutes of Health Stroke Scale.