Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology · 2002
[The study of correlation between HPV and vocal cord polyp].
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Lian Bing, Wang Jiqun, Wang Lihua
Аннотация
OBJECTIVE: To reveal the correlation between HPV and human vocal cord polyp (vcp).
METHOD: Analyzed the morphological changes of 99 vocal cord polyps stained with HE by microscope and 11 specimen by transmission electron microscopy and scanning electron microscopy; Meanwhile, HPV-DNA were detected in 50 vcp by PCR, and then a comparison analysis with the pathological results of vcp was made.
RESULT: Koilocytoid cells were observed in 55 of 99 vcp (55.6%); The presence of HPV-DNA were detected in 34 of 50 vcp (68%), HPV-DNA positive rate was 92.9% and 36.4% respectively in 34 cases with koilocyte-like cells expression and 22 cases without koilcyte-like cells expression; there was significant different. The results of electron microscopy agreed with the results under light microscopy except koilocyte-like cell expression.
CONCLUSION: There is obvious correlation between HPV and vcp, HPV may play certain role in the occurrence of vcp.
METHOD: Analyzed the morphological changes of 99 vocal cord polyps stained with HE by microscope and 11 specimen by transmission electron microscopy and scanning electron microscopy; Meanwhile, HPV-DNA were detected in 50 vcp by PCR, and then a comparison analysis with the pathological results of vcp was made.
RESULT: Koilocytoid cells were observed in 55 of 99 vcp (55.6%); The presence of HPV-DNA were detected in 34 of 50 vcp (68%), HPV-DNA positive rate was 92.9% and 36.4% respectively in 34 cases with koilocyte-like cells expression and 22 cases without koilcyte-like cells expression; there was significant different. The results of electron microscopy agreed with the results under light microscopy except koilocyte-like cell expression.
CONCLUSION: There is obvious correlation between HPV and vcp, HPV may play certain role in the occurrence of vcp.