Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology · 2006
[Expression of BDNF and trk B in the cochleas of the aged rats].
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Li Yuru, Liu Delong, Zhang Yuanyuan, Wang Ping, Du Baodong
Аннотация
OBJECTIVE: To explore the correlation between the expression of brain derived neurotrophic factor (BDNF) and presbycusis in the cochleae of the aged rats.
METHOD: The mRNA expression of BDNF and presbycusis in the cochleas of the aged rats was quantitated by real time PCR.
RESULT: The expression of BDNF in the cochleas of the aged rats with presbycusis was obviously less than that in the control group. And the difference was statistically significant.
CONCLUSION: The expression of BDNF is closely correlated to presbycusis in the aged rats.
METHOD: The mRNA expression of BDNF and presbycusis in the cochleas of the aged rats was quantitated by real time PCR.
RESULT: The expression of BDNF in the cochleas of the aged rats with presbycusis was obviously less than that in the control group. And the difference was statistically significant.
CONCLUSION: The expression of BDNF is closely correlated to presbycusis in the aged rats.