Pancreas · 2026
Association of Pain With Healthcare Use and Indirect Burden in Pediatric Acute, Recurrent, and Chronic Pancreatitis.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Li Rui, Murray Caitlin B, Aalfs Homer, Lowe Mark, Uc Aliye, Palermo Tonya M
Аннотация
OBJECTIVES: Abdominal pain affects nearly 80% of youth with acute recurrent or chronic pancreatitis (ARP/CP), yet its broader burden is poorly understood. We characterized direct (healthcare utilization) and indirect (school absenteeism, parental work loss) burden in youth with painful ARP/CP and examined associations with pain characteristics and health-related quality of life (HRQOL).
METHODS: Youth with painful ARP/CP and caregivers were recruited from INSPPIRE sites and the community. Caregivers reported healthcare use and indirect burden using the Client Service Receipt Inventory. Youth completed validated measures of pain severity, pain interference, and HRQOL. Negative binomial and logistic regression assessed associations between pain, HRQOL, and disease burden.
RESULTS: Ninety youth (mean age=14.9) were included. Over 9 months, youth had a median of 1 hospital admission (3 -nights stay), 1.5 ED visits, 4 outpatient visits, 1 non-physician service type, 18.5 missed school days, and 6.0 parental workdays lost; 1 in 6 parents provided additional weekly childcare. Higher pain severity was associated with higher ED (+33%) and outpatient visits (+20%), more medication use (+35%), complementary and alternative medicine (CAM) use (+136%), and more school days missed (+48%). Higher pain interference was linked to more hospital admissions (+38%) and longer stays (+103%), greater outpatient (+21%), non-physician (+20%), CAM (+120%), medication use (+41%; opioids +138%), and more school (+100%) and parental workday loss (+133%). Higher HRQOL was associated with lower burden.
CONCLUSIONS: Pediatric painful ARP/CP imposes a substantial direct and indirect burden. Interventions targeting pain and disability may reduce healthcare use and improve functioning and family well-being.
METHODS: Youth with painful ARP/CP and caregivers were recruited from INSPPIRE sites and the community. Caregivers reported healthcare use and indirect burden using the Client Service Receipt Inventory. Youth completed validated measures of pain severity, pain interference, and HRQOL. Negative binomial and logistic regression assessed associations between pain, HRQOL, and disease burden.
RESULTS: Ninety youth (mean age=14.9) were included. Over 9 months, youth had a median of 1 hospital admission (3 -nights stay), 1.5 ED visits, 4 outpatient visits, 1 non-physician service type, 18.5 missed school days, and 6.0 parental workdays lost; 1 in 6 parents provided additional weekly childcare. Higher pain severity was associated with higher ED (+33%) and outpatient visits (+20%), more medication use (+35%), complementary and alternative medicine (CAM) use (+136%), and more school days missed (+48%). Higher pain interference was linked to more hospital admissions (+38%) and longer stays (+103%), greater outpatient (+21%), non-physician (+20%), CAM (+120%), medication use (+41%; opioids +138%), and more school (+100%) and parental workday loss (+133%). Higher HRQOL was associated with lower burden.
CONCLUSIONS: Pediatric painful ARP/CP imposes a substantial direct and indirect burden. Interventions targeting pain and disability may reduce healthcare use and improve functioning and family well-being.