Cochlear size variation in a large-scale international multicentre cohort.
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Schreier Andrea, Zernotti Mario, Acharya Aanand, Eisenberg Robert, Sahwan Maryam, Alshehabi Mohamed, Van Rompaey Vincent, Lammers Marc, Dhanasingh Anandhan, Chen Suijun, Hui Lian, Mustafa Ahmed, Feky Nader El, Alshamsi Ahmed, Alamadi Ahmad, Schmerber Sebastian, Godey Benoit, Bilson-Amoah Estella, Virk Ramandeep, Swami Himanshu, Kumari Abha, Usami Shin-Ichi, Yoshimura Hidekane, Mwangi Grace, Ndegwa Serah, Al-Sihan Mutlaq, Alkandari Mariam, Adeyemo Adekunle, Zaabi Khalid Al, Tamami Nasser Al, Skarzynski Piotr Henryk, Walkowiak Adam, Sugarova Sima, Kuzovkov Vladislav, Almuhawas Fida, Altamami Fahad N, Alonso Cristina, Lassaletta Luis, Hofmeyr Louis, Ahmed Mohamed Razwi Ismail, Burden Elnemarie, Grobbelaar Johan, Mawala Shaban, Jaffer Ali F, Seguya Amina, Jones Linor, Flook Edward, Selleck Anne Morgan, Dunn Camille, Lin James, Müller-Goebel Justus, Müller Joachim
Аннотация
METHODS: A scoping literature review was conducted using the search term "diameter of cochlear basal turn" to identify studies reporting A-value measurements. To complement this, cochlear measurements obtained with OTOPLAN® were collected from clinical collaborators across multiple international centres. The ratio of B- to A-values, which defines the cochlear basal turn shape, was calculated as previously described by Khurayzi et al. (2021).
RESULTS: The literature review identified 38 studies comprising 5,206 A-value measurements (average: 9.08 mm; range: 8.01-10.03 mm). Additionally, 5,580 OTOPLAN® measurements were collected from 43 clinics across 25 countries (mean: 9.07 mm; range: 6.67-11.45 mm). Overall, 68.7% of cochleae exhibited an elliptical basal turn shape.
CONCLUSION: Using a large, international multicentre dataset and a standardized measurement tool, this study demonstrates substantial variation in cochlear size and shape across clinical cohorts from different regions. The mean A-value (9.07 mm) is consistent with previously published literature, while the wider observed range highlights greater anatomical variability within a multicentre clinical population than previously reported. The majority of cochleae demonstrate an elliptical basal turn configuration.