Медицинская библиотека · Khirurgiia · 2020

[Liver transplantation for hepatoblastoma in children].

Filin A V, Kim E F, Charchyan E R, Metelin A V, Dymova O V, Kachanov D Yu, Moiseenko R A, Khovrin V V, Kryzhanovskaya E Yu, Kazakova O V, Ryabov A B, Bazarov D V

СтатьяОригинал на русском

Аннотация

OBJECTIVE

To improve the outcomes in children with hepatoblastoma.

MATERIAL AND

METHODS

There were 160 children with focal liver lesions who underwent surgery at the department of liver transplantation in 2008-2019. Patients with malignant tumors made up 77% (n=123). Hepatoblastoma (HB) prevailed (86%, n=106). Liver transplantation was performed in 19 (18%) patients with HB. Median follow-up after transplantation was 24.3 months by December 2019. Follow-up period did not exceed 4 years in more than 2/3 of patients.

RESULTS

Overall and disease-free 10-year survival was 87.1% and 82.7%, respectively. Similar values were observed after resections (91.1% and 86.6%). At the same time, actuarial 4-year survival after liver transplantation for HB was 68%.

CONCLUSION

Improvement of treatment outcomes may be achieved through multidisciplinary interaction ensuring timely drug therapy and liver transplantation.

Для цитирования: Filin A V, Kim E F, Charchyan E R, Metelin A V, Dymova O V, Kachanov D Yu, Moiseenko R A, Khovrin V V, Kryzhanovskaya E Yu, Kazakova O V, Ryabov A B, Bazarov D V. [Liver transplantation for hepatoblastoma in children].. Khirurgiia. 2020. DOI: 10.17116/hirurgia20201115.

Предметные рубрики MeSH

Child Combined Modality Therapy Hepatectomy Hepatoblastoma Humans Infant Liver Neoplasms Liver Transplantation Retrospective Studies Treatment Outcome

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