Hereditary spherocytosis in Nigerians.

Five cases of hereditary spherocytosis in Nigerians are discussed. The clinical presentation and haematological abnormalities are similar to those described in other parts of the world. In one patient family studies were negative. The series does not permit a gene frequency estimate for the country but the cases came from widely separated area, suggesting that no ethnic group has more predilection than others. Splenectomy was uniformly successful.