Serum zinc and copper levels in sickle cell anaemia and beta-thalassaemia in North Jordan.

Serum zinc and copper levels were determined in 28 beta-thalassaemia and 15 sickle cell anaemia (SCA) patients of 3-10 years of age using atomic absorption spectrophotometry. The results were compared with 25 age-matched controls. Copper levels were significantly increased in beta-thalassaemia and sickle cell anaemia. Zinc levels were significantly increased in beta-thalassaemia but significantly decreased in SCA. The data suggest the occurrence of impaired kidney function and disturbance in the metabolism of zinc and copper in these patients.