Intensive care medicine · 1993
Resistance to methicillin and virulence of Staphylococcus aureus strains in bacteriemic cancer patients.
Сравнительное исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Marty L, Flahault A, Suarez B, Caillon J, Hill C, Andremont A
Аннотация
OBJECTIVE: To estimate the relation between resistance to methicillin and virulence in strains of Staph. aureus by estimating the survival at day 30.
DESIGN: Case control analysis.
SETTING: Inpatients at a major Cancer Referral Center.
PATIENTS: 21 patients with methicillin-resistant Staph. aureus (MRSA) bactaeremia and 45 patients with methicillin-susceptible Staph. aureus (MSSA) bactaeremia, all treated with vancomycin.
MEASUREMENTS AND MAIN RESULTS: Fewer MRSA than MSSA patients were neutropenic (p = 0.04), but more MRSA patients were hospitalized in intensive care units (p = 0.03), had had surgical episodes (p = 0.06). MRSA patients also had more microbiological samples cultured (p = 0.007). The outcome of the bacteriemic episodes in 14 MRSA and 14 MSSA patients matched for these four factors showed that blood cultures from MRSA patients remained positive significantly longer (p = 0.04), but that survival and length of hospital stay were not significantly different.
CONCLUSIONS: These results do not indicate that methicillin-resistance in Staph. aureus is associated with increased virulence.
DESIGN: Case control analysis.
SETTING: Inpatients at a major Cancer Referral Center.
PATIENTS: 21 patients with methicillin-resistant Staph. aureus (MRSA) bactaeremia and 45 patients with methicillin-susceptible Staph. aureus (MSSA) bactaeremia, all treated with vancomycin.
MEASUREMENTS AND MAIN RESULTS: Fewer MRSA than MSSA patients were neutropenic (p = 0.04), but more MRSA patients were hospitalized in intensive care units (p = 0.03), had had surgical episodes (p = 0.06). MRSA patients also had more microbiological samples cultured (p = 0.007). The outcome of the bacteriemic episodes in 14 MRSA and 14 MSSA patients matched for these four factors showed that blood cultures from MRSA patients remained positive significantly longer (p = 0.04), but that survival and length of hospital stay were not significantly different.
CONCLUSIONS: These results do not indicate that methicillin-resistance in Staph. aureus is associated with increased virulence.
Предметные рубрики MeSH
AdolescentAdultAgedBacteremiaCancer Care FacilitiesCase-Control StudiesChildChild, PreschoolFemaleHumansInfantInfant, NewbornIntensive Care UnitsLength of StayMaleMatched-Pair AnalysisMethicillin ResistanceMiddle AgedNeoplasmsNeutropeniaPrognosisReferral and ConsultationStaphylococcal InfectionsStaphylococcus aureusSurvival AnalysisSurvival RateVancomycin