Bridging metabolic-cognitive modelling: from synaptic cost to functional brain organisation.

Haueis and Colaço argue that metabolism is a generative principle for cognitive modelling. We extend this by bridging the "scaling gap" through functional PET (fPET) and network neuroscience. By measuring glucodynamics and the metabolic network of the brain, we can model how glucose metabolism enables network efficiency, temporal flexibility, information transfer, and ultimately the cognitive capacity of the human brain.