Results of an etiological therapy applied to patients with different localizations of herpes infection detected by immunofluorescence reaction.

An indirect immunofluorescence reaction was used for cytovirological diagnosis in 110 patients with different herpes-like clinical manifestations. The presence of herpes antigens type 1 and 2 was made evident in the exfoliated cells from 77% of the cases with recurrent herpes, in 68% of those with cutaneous and/or oral herpes, in 64% of the cases with keratoconjunctivitis and in 37.5% of the women with different genital diseases. Administration of specific antiherpes immunoglobulins and of the chemotherapeutic drug Flumidin to cases with positive immunofluorescence reactions led to improvement of the symptoms and even to clinical recovery.