Epidemiological characteristics of Circovirus Human infection in hospitalized patients in a representative infectious disease hospital in Guangzhou, China, from Feb 2023 to Dec 2024.

Circovirus Human reported in recent years have drawn attention as potential human pathogens in susceptible patients. However, its epidemiological characteristics are less investigated. We found 3 infected cases in 1330 hospitalized patients with suspected unidentified infections in a designated hospital for treating infectious diseases by retrospectively analyzing their metagenomic sequencing data. All three patients were HIV-positive and immunosuppressed. Liver function tests were normal at admission but showed transient acute injury during antimicrobial therapy, without hepatitis virus coinfection.