[Analysis of the causes of the predominant localization of macular cerebral vessel and tissue lesions following an acute rise in arterial pressure].

In acute experiment on rabbits a rise in arterial pressure was induced by intravenous administration of noradrenaline with simultaneous recording of the changes in the vessel diameter on the surface of the brain in arterial bordering zones and in the basin of the middle cerebral artery and permeability of the hematoencephalic barrier to Evans blue. Autoregulation disorder manifesting itself in dilatation of the arteries and spreading out of their enternal elastic membrane developed first of all in arterial bordering zones, appeared earlier and was marked mainly in the anastomoses of the major type and small arteries lying at an acute angle which are more often detected in the occipital regions of the blood supply area. Similar results were obtained with an analysis of 3-section cases of hypertensive encephalopathy.