[Prefrontal dementias: clinical features and SPECT in 6 cases].

Six patients with primary degenerative dementias and frontal or frontotemporal hypoperfusion are reported. Five were diagnosed as Frontal Progressive Dementia (FPD), characterized by striking changes in personality and social behavior. The last patient had a progressive aphasia and a moderate cognitive impairment. We discuss the heterogeneity of FPD that includes Pick's disease, frontal lobe type dementia (Neary) and progressive subcortical gliosis. The usefulness of SPECT and the need of a brain bank are remarked.