Increased 18 F-AV1451 Retention in Soft Tissue of Patients With Progressive Supranuclear Palsy.

We report 18 F-AV1451 PET/MRI findings of a 56-year-old man with progressive supranuclear palsy (PSP). The images revealed multifocal 18 F-AV1451 tracer uptake in both intracranial and extracranial regions, with increased retention in bilateral basal ganglia regions and scalp soft tissue. The findings may reflect systemic tau pathology and provide the clinical experience for the possible assessment of the disease severity.