Canadian journal of surgery. Journal canadien de chirurgie · 2001
Isolated limb infusion for melanoma: a simple alternative to isolated limb perfusion.
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Mian R, Henderson M A, Speakman D, Finkelde D, Ainslie J, McKenzie A
Аннотация
OBJECTIVE: To describe initial experience with the new technique of isolated limb infusion (ILI) for in-transit melanoma.
DESIGN: A prospective case series.
SETTING: The major tertiary care oncology centre for the state of Victoria, Australia.
PATIENTS: Nine patients having for extensive in-transit limb melanoma
INTERVENTIONS: All patients received ILI (13 treatments).
OUTCOME MEASURES: Patient survival, response to treatment and complications of treatment.
RESULTS: There were no perioperative deaths and morbidity was limited to deep venous thrombosis and pulmonary embolism in 1 patient. Control of the in-transit metastases was achieved to some degree in all patients and was complete in 4.
CONCLUSIONS: ILI is an alternative treatment modality for patients suffering from multiple, advanced in-transit melanoma metastases. It provides effective palliation with limited morbidity and offers a safe, quick, inexpensive alternative to isolated limb perfusion with comparable results.
DESIGN: A prospective case series.
SETTING: The major tertiary care oncology centre for the state of Victoria, Australia.
PATIENTS: Nine patients having for extensive in-transit limb melanoma
INTERVENTIONS: All patients received ILI (13 treatments).
OUTCOME MEASURES: Patient survival, response to treatment and complications of treatment.
RESULTS: There were no perioperative deaths and morbidity was limited to deep venous thrombosis and pulmonary embolism in 1 patient. Control of the in-transit metastases was achieved to some degree in all patients and was complete in 4.
CONCLUSIONS: ILI is an alternative treatment modality for patients suffering from multiple, advanced in-transit melanoma metastases. It provides effective palliation with limited morbidity and offers a safe, quick, inexpensive alternative to isolated limb perfusion with comparable results.