Ocular immunology and inflammation · 2017
The Pattern of Uveitis in Sri Lanka.
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Siak Jay, Kumaradas Mirna, Chee Soon-Phaik
Аннотация
PURPOSE: To describe the pattern of uveitis at a tertiary uveitis referral clinic in Sri Lanka.
METHODS: Consecutive charts identified from a registry between January 2010 and December 2014 at the Mediclinic Hospital, Colombo were retrospectively reviewed.
RESULTS: Among 750 patients, anterior uveitis (AU) was the most common (285, 38%), followed by posterior uveitis (187, 25%), intermediate uveitis (150, 20%), and panuveitis (128, 17%). 485 (65%) were idiopathic. The top identified causes of AU were seronegative-spondyloarthropathy-related-AU (37, 13%), HLA-B27-related-AU without systemic associations (25, 9%), herpetic-AU (18, 6%), and trematode uveitis (8, 3%). The main posterior uveitis were toxoplasmosis (34, 18%), tuberculosis (21, 11%), and sarcoidosis (17, 9%). 78% of intermediate uveitis were idiopathic, with 12 (8%) tuberculosis, and 10 (7%) sarcoidosis. The most common panuveitis were sarcoidosis (18, 14%), tuberculosis (14, 11%), and Vogt-Koyanagi-Harada disease (10, 8%). Among children (≤12 years) accounting for 25 (3%) of cases, the most common presentations were idiopathic intermediate uveitis (7, 28%), idiopathic-AU (4, 16%), toxoplasmosis (4, 16%), trematode uveitis (3, 12%), and toxocariasis (2, 8%).
CONCLUSIONS: An infectious etiology must be considered in posterior uveitis and uveitis among children in the Sri Lankan population.
METHODS: Consecutive charts identified from a registry between January 2010 and December 2014 at the Mediclinic Hospital, Colombo were retrospectively reviewed.
RESULTS: Among 750 patients, anterior uveitis (AU) was the most common (285, 38%), followed by posterior uveitis (187, 25%), intermediate uveitis (150, 20%), and panuveitis (128, 17%). 485 (65%) were idiopathic. The top identified causes of AU were seronegative-spondyloarthropathy-related-AU (37, 13%), HLA-B27-related-AU without systemic associations (25, 9%), herpetic-AU (18, 6%), and trematode uveitis (8, 3%). The main posterior uveitis were toxoplasmosis (34, 18%), tuberculosis (21, 11%), and sarcoidosis (17, 9%). 78% of intermediate uveitis were idiopathic, with 12 (8%) tuberculosis, and 10 (7%) sarcoidosis. The most common panuveitis were sarcoidosis (18, 14%), tuberculosis (14, 11%), and Vogt-Koyanagi-Harada disease (10, 8%). Among children (≤12 years) accounting for 25 (3%) of cases, the most common presentations were idiopathic intermediate uveitis (7, 28%), idiopathic-AU (4, 16%), toxoplasmosis (4, 16%), trematode uveitis (3, 12%), and toxocariasis (2, 8%).
CONCLUSIONS: An infectious etiology must be considered in posterior uveitis and uveitis among children in the Sri Lankan population.