Journal of vascular and interventional radiology : JVIR · 2025
Diagnostic Accuracy and Clinical Impact of Ultrasound-Guided Percutaneous Lung Biopsy in Pediatric Patients: A Retrospective Observational Study.
СтатьяНаблюдательное исследованиеНазвание и аннотация: Перевод пока не подготовлен
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Ding Jiaojiao, Ni Xin, Zhang Xiao, Wan Jiabin, Shi Wenyuan
Аннотация
PURPOSE: To evaluate the diagnostic accuracy, safety, and clinical impact of ultrasound-guided percutaneous lung biopsy (US-PLB) in pediatric peripheral lung lesions.
MATERIALS AND METHODS: A retrospective cohort analysis included 34 pediatric patients (24 boys; 10 girls; mean age, 7.9 years [SD ± 4.4]) who underwent US-PLB from March 2019 to February 2024. Diagnostic metrics (sensitivity, specificity, and positive and negative predictive values) and adverse events were analyzed. The influence of biopsy results on clinical management was assessed.
RESULTS: Among 33 diagnostic procedures, US-PLB demonstrated an accuracy of 97.0% (32/33), with a sensitivity of 80.0% (4/5 malignant lesions) and specificity of 100% (28/28 benign lesions). Minor complications occurred in 17.6% (6/34) of patients, including pneumothorax (2.9%) and transient hemoptysis (2.9%). Biopsy findings directly altered therapeutic strategies in 44.1% (15/34) of cases, including initiation of chemotherapy or targeted antimicrobial therapy.
CONCLUSIONS: US-PLB is a safe and accurate radiation-free diagnostic technique for pediatric peripheral lung lesions, offering critical histopathologic and microbiologic guidance for clinical decision making.
MATERIALS AND METHODS: A retrospective cohort analysis included 34 pediatric patients (24 boys; 10 girls; mean age, 7.9 years [SD ± 4.4]) who underwent US-PLB from March 2019 to February 2024. Diagnostic metrics (sensitivity, specificity, and positive and negative predictive values) and adverse events were analyzed. The influence of biopsy results on clinical management was assessed.
RESULTS: Among 33 diagnostic procedures, US-PLB demonstrated an accuracy of 97.0% (32/33), with a sensitivity of 80.0% (4/5 malignant lesions) and specificity of 100% (28/28 benign lesions). Minor complications occurred in 17.6% (6/34) of patients, including pneumothorax (2.9%) and transient hemoptysis (2.9%). Biopsy findings directly altered therapeutic strategies in 44.1% (15/34) of cases, including initiation of chemotherapy or targeted antimicrobial therapy.
CONCLUSIONS: US-PLB is a safe and accurate radiation-free diagnostic technique for pediatric peripheral lung lesions, offering critical histopathologic and microbiologic guidance for clinical decision making.