Salud publica de Mexico · 2008
Serotypes and susceptibility of Streptococcus pneumoniae strains isolated from children in Mexico.
СтатьяПоддержка NIH: внешняя программаНазвание и аннотация: Перевод пока не подготовлен
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Villaseñor-Sierra Alberto, Lomas-Bautista Maricarmen, Aguilar-Benavides Sergio, Martínez-Aguilar Gerardo
Аннотация
OBJECTIVE: To identify serotypes and susceptibility of S. pneumoniae strains from 48 children with invasive infections and 50 carriers.
MATERIAL AND METHODS: Typing was performed by the Quellung reaction and susceptibility by Kirby-Bauer and Etest according to CLSI standards.
RESULTS: Of 31 meningeal strains, serotypes 19F, 3, 6B, 14 and 23F were predominant. Resistance to penicillin and STX was 16 and 58%, respectively; of 17 invasive non-meningeal strains, serotypes 19F and 3 were predominant and resistance to penicillin and SXT was 0 and 82%, respectively; of carrier strains, serotypes 6A, 6B, 19F and 23F were predominant.
CONCLUSIONS: A 10-valent conjugate vaccine could offer a better coverage for meningeal strains.
MATERIAL AND METHODS: Typing was performed by the Quellung reaction and susceptibility by Kirby-Bauer and Etest according to CLSI standards.
RESULTS: Of 31 meningeal strains, serotypes 19F, 3, 6B, 14 and 23F were predominant. Resistance to penicillin and STX was 16 and 58%, respectively; of 17 invasive non-meningeal strains, serotypes 19F and 3 were predominant and resistance to penicillin and SXT was 0 and 82%, respectively; of carrier strains, serotypes 6A, 6B, 19F and 23F were predominant.
CONCLUSIONS: A 10-valent conjugate vaccine could offer a better coverage for meningeal strains.