Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology · 2005
MRI evaluation of neurofibromatosis 2 patients: a standardized approach for accuracy in interpretation.
СтатьяМногоцентровое исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Slattery William H, Lev Michael H, Fisher Laurel M, Connell Sarah S, Iqbal Zarina, Go John L, NF2 Natural History Consortium
Аннотация
OBJECTIVE: To determine the level of agreement between local radiologists' and an experienced neuroradiologist's measurements of vestibular schwannomas.
STUDY DESIGN: Prospective study with uniform magnetic resonance acquisition protocol parameters and reporting instructions across 30 magnetic resonance imaging facilities worldwide.
SETTING: Multicenter natural history study of neurofibromatosis Type 2.
SUBJECTS: One hundred fifteen magnetic resonance imaging examinations of 57 neurofibromatosis Type 2 patients older than 5 years of age.
INTERVENTIONS: Thin-slice, postcontrast cranial magnetic resonance imaging.
MAIN OUTCOME MEASURES: Spearman's rho interobserver association coefficient of vestibular schwannoma linear measurements.
RESULTS: The local and experienced radiologist measurements and identification of tumors agreement was fair (kappa = 0.77). Discordant interpretations were adjudicated by another experienced neuroradiologist.
CONCLUSION: The least interobserver variability was found in measurements of thin-slice postcontrast magnetic resonance imaging scans obtained at neurofibromatosis Type 2 centers in patients without previous operations and moderately sized tumors. If the schwannoma was difficult to assess, because of magnetic resonance imaging acquisition protocol, postoperative changes, or tumors smaller than 5 mm in greatest diameter, the neuroradiologist provided a more thorough assessment. The authors suggest uniform reporting criteria for vestibular schwannoma assessments to ensure clinically relevant information is communicated regarding vestibular schwannoma size.
STUDY DESIGN: Prospective study with uniform magnetic resonance acquisition protocol parameters and reporting instructions across 30 magnetic resonance imaging facilities worldwide.
SETTING: Multicenter natural history study of neurofibromatosis Type 2.
SUBJECTS: One hundred fifteen magnetic resonance imaging examinations of 57 neurofibromatosis Type 2 patients older than 5 years of age.
INTERVENTIONS: Thin-slice, postcontrast cranial magnetic resonance imaging.
MAIN OUTCOME MEASURES: Spearman's rho interobserver association coefficient of vestibular schwannoma linear measurements.
RESULTS: The local and experienced radiologist measurements and identification of tumors agreement was fair (kappa = 0.77). Discordant interpretations were adjudicated by another experienced neuroradiologist.
CONCLUSION: The least interobserver variability was found in measurements of thin-slice postcontrast magnetic resonance imaging scans obtained at neurofibromatosis Type 2 centers in patients without previous operations and moderately sized tumors. If the schwannoma was difficult to assess, because of magnetic resonance imaging acquisition protocol, postoperative changes, or tumors smaller than 5 mm in greatest diameter, the neuroradiologist provided a more thorough assessment. The authors suggest uniform reporting criteria for vestibular schwannoma assessments to ensure clinically relevant information is communicated regarding vestibular schwannoma size.