Accuracy of Intraocular Lens Power Calculation Formulas in Cataract Eyes after Vitrectomy with Silicone Oil Tamponade: A Network Meta-Analysis.

INTRODUCTION

The aim of the study was to systematically compare the accuracy of artificial intelligence and traditional intraocular lens (IOL) calculation formulas in cataract eyes after vitrectomy with silicone oil tamponade.

METHODS

PubMed, Cochrane, Embase, and Web of Science databases were searched to select relevant studies published up to October 29, 2025. A total of 12 formulas (SRK/T, Hoffer Q, Hoffer QST, Haigis, Barrett Universal II, Holladay I, Holladay II, RBF, LSF, EVO, Kane, and Pearl-DGS) were included for final comparison. The primary outcomes were the percentage of eyes with prediction errors (PE) within ± 0.50 D and ± 1.00 D.

RESULTS

This meta-analysis included 7 studies comprising 1,060 eyes. Overall, compared to traditional formulas, newer formulas demonstrated relatively higher accuracy. The results indicated that among all the formulas being compared, the optimal formula was Kane. For the percentage of eyes with PE within ± 0.50 D, Kane had the highest precision. For the IOL power percentage within ± 1.00 D, EVO performed the best, with Kane also ranking highly. Furthermore, RBF also performed very well.

CONCLUSION

Kane and EVO appear to be better choices for silicone oil-filled eyes after vitrectomy.