Retina (Philadelphia, Pa.) · 2011
Endophthalmitis caused by Pseudomonas aeruginosa in Taiwan.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
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Chen Kuan-Jen, Sun Ming-Hui, Lai Chi-Chun, Wu Wei-Chi, Chen Tun-Lu, Kuo Ya-Hui, Chao An-Ning, Hwang Yih-Shiou, Chen Yen-Po, Wang Nan-Kai, Liu Laura, Kuo Jane Zea-Chin
Аннотация
PURPOSE: To investigate the clinical settings, treatment given, and visual outcomes for eyes with Pseudomonas aeruginosa endophthalmitis in Taiwan.
METHODS: This is a retrospective, noncomparative, consecutive case series. Medical records were reviewed in 72 eyes of 71 patients with culture-proven P. aeruginosa endophthalmitis between January 1997 and December 2007.
RESULTS: The clinical settings included keratitis/scleritis (44.4%), cataract surgery (15.3%), penetrating keratoplasty (13.9%), endogenous source (12.5%), trauma (6.9%), penetrating keratoplasty with cataract surgery (2.8%), trabeculectomy with cataract surgery (1.4%), trabeculectomy (1.4%), and secondary implant (1.4%). Initial visual acuity ranged from counting fingers to no light perception. Final visual acuity was better than 5/200 in 6 of 72 eyes (8.3%), 4/200 to hand motions in 4 eyes (5.6%), and light perception to no light perception in 62 eyes (86.1%). In vitro testing, the susceptibility patterns of organisms isolated were as follows: ceftazidime (100%), cefepime (100%), aztreonam (100%), imipenem (99%), amikacin (94%), and gentamicin (86%). Five of 16 eyes (31.3%) that underwent primary or secondary pars plana vitrectomy with intravitreal antibiotics achieved a final visual acuity of 5/200 or better compared with 1 of 45 eyes (2.2%) treated with 1 or multiple vitreous tap(s) and intravitreal antibiotics (Fisher's exact test, P = 0.004).
CONCLUSION: Despite early diagnosis and treatment with intravitreal antibiotics, visual acuity outcomes were generally poor.
METHODS: This is a retrospective, noncomparative, consecutive case series. Medical records were reviewed in 72 eyes of 71 patients with culture-proven P. aeruginosa endophthalmitis between January 1997 and December 2007.
RESULTS: The clinical settings included keratitis/scleritis (44.4%), cataract surgery (15.3%), penetrating keratoplasty (13.9%), endogenous source (12.5%), trauma (6.9%), penetrating keratoplasty with cataract surgery (2.8%), trabeculectomy with cataract surgery (1.4%), trabeculectomy (1.4%), and secondary implant (1.4%). Initial visual acuity ranged from counting fingers to no light perception. Final visual acuity was better than 5/200 in 6 of 72 eyes (8.3%), 4/200 to hand motions in 4 eyes (5.6%), and light perception to no light perception in 62 eyes (86.1%). In vitro testing, the susceptibility patterns of organisms isolated were as follows: ceftazidime (100%), cefepime (100%), aztreonam (100%), imipenem (99%), amikacin (94%), and gentamicin (86%). Five of 16 eyes (31.3%) that underwent primary or secondary pars plana vitrectomy with intravitreal antibiotics achieved a final visual acuity of 5/200 or better compared with 1 of 45 eyes (2.2%) treated with 1 or multiple vitreous tap(s) and intravitreal antibiotics (Fisher's exact test, P = 0.004).
CONCLUSION: Despite early diagnosis and treatment with intravitreal antibiotics, visual acuity outcomes were generally poor.
Предметные рубрики MeSH
AdultAgedAged, 80 and overAnti-Bacterial AgentsCataract ExtractionCorneal UlcerEndophthalmitisEye Infections, BacterialFemaleHumansKeratoplasty, PenetratingMaleMicrobial Sensitivity TestsMiddle AgedPseudomonas InfectionsPseudomonas aeruginosaRetrospective StudiesScleritisTaiwanTrabeculectomyVisual Acuity