Celiac disease in children with focus on symptoms and quality of life.

The treatment for celiac disease (CD) consist of adhering to a gluten-free diet (GFD). Studies have reported that an appropriate and close nutritional assessment would be beneficial in improving symptoms and quality of life (QoL). This study investigated the effect of a nutritional intervention on the evolution of gastrointestinal (GI) and extraintestinal (EI) symptoms in children newly diagnosed with CD, and its association with QoL. 46 children who had recently been diagnosed with CD were followed up on three occasions during the year: at the time of diagnosis, and after 3 and 12 months (vt0, vt3 and vt12). Participants completed questionnaires on GI- and an EI-symptom, QoL and diet. Recovery was assessed based on clinical improvement and serological response. FODMAP consumption was analysed as a possible cause of symptoms. All patients received dietary advice and face-to-face follow-up. Although following a GFD is beneficial for symptom remission, recovery varies between patients. However, following a GFD is not sufficient to achieve a good QoL, with overall scores suggesting that participants have a poor QoL. Their parents/carers also have this perception. FODMAP consumption cannot be associated with a reduction in symptoms. Follow-up and nutritional education are important for improving GI and EI symptoms. However, more effort is needed to improve QoL in children with CD.