Klinicheskaia laboratornaia diagnostika · 1996
[The activity of trypsin and proteolytic inhibitors in complicated forms of appendicitis in children].
Сравнительное исследованиеАннотация на английскомСтатьяНазвание и аннотация: Оригинал на русском
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Sukhanova G A, Shalbueva N I, Shalygin V A
Аннотация
The activity of trypsin, alpha 1-proteinase inhibitor, and alpha 2-macroglobulin (MG) was measured in the blood plasma of patients with destructive appendicitis and localized and generalized peritonitis during admission to hospital and for 3 weeks after surgery. A deficit of MG was found in all forms of these diseases. A decreased activity of MG in the blood plasma is apparently a risk factor for emergency inflammatory diseases of abdominal organs. After appendectomy a more demonstrative index of patient's status is trypsin activity, an increase of which is most of all expressed in generalized peritonitis. Quantitative assessment of the trypsin-inhibitor system activity before and after surgery is necessary for a more accurate diagnosis and for monitoring the quality of treatment.