The Pediatric infectious disease journal · 2008
Flexible bronchoscopy for diagnosis and follow up of childhood endobronchial tuberculosis.
Клиническое исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Cakir Erkan, Uyan Zeynep Seda, Oktem Sedat, Karakoc Fazilet, Ersu Refika, Karadag Bulent, Dagli Elif
Аннотация
BACKGROUND: In this study, our aim was to determine the clinical and bronchoscopic outcome of the endobronchial tuberculosis (ETB).
METHODS: Patients with suspected tuberculosis (TB) or TB patients with an inadequate response to 8 weeks of antituberculosis treatment were enrolled in the study.
RESULTS: Seventy patients were included to the study and 118 flexible bronchoscopies were performed. ETB was present in 33 (47%) patients. There was isolated compression in 14 cases, caseous lesions in 13, granuloma formation in 6, polypoid lesions in 2, adenopathy protrusion in 1, and mucosal erosion in 1 case. The mean duration of bronchoscopic resolution of endobronchial lesions was 5.50 +/- 2.74 months. Mycobacterium tuberculosis was isolated from gastric lavage in 10% and from bronchoalveolar lavage in 12.8% of 70 cases. When both of the procedures were performed concurrently, the isolation rate increased to 20%. Transient hypoxia resolving with nasal O2 was observed in 3 patients as a complication of bronchoscopy.
CONCLUSIONS: Bronchoscopy offered a safe and rapid means of confirming the diagnosis of ETB.
METHODS: Patients with suspected tuberculosis (TB) or TB patients with an inadequate response to 8 weeks of antituberculosis treatment were enrolled in the study.
RESULTS: Seventy patients were included to the study and 118 flexible bronchoscopies were performed. ETB was present in 33 (47%) patients. There was isolated compression in 14 cases, caseous lesions in 13, granuloma formation in 6, polypoid lesions in 2, adenopathy protrusion in 1, and mucosal erosion in 1 case. The mean duration of bronchoscopic resolution of endobronchial lesions was 5.50 +/- 2.74 months. Mycobacterium tuberculosis was isolated from gastric lavage in 10% and from bronchoalveolar lavage in 12.8% of 70 cases. When both of the procedures were performed concurrently, the isolation rate increased to 20%. Transient hypoxia resolving with nasal O2 was observed in 3 patients as a complication of bronchoscopy.
CONCLUSIONS: Bronchoscopy offered a safe and rapid means of confirming the diagnosis of ETB.