A case-control study of risk factors for proliferative vitreoretinopathy in aphakia.

A case-control study was performed to elucidate the risk factors of proliferative vitreoretinopathy (PVR) in aphakia. Twenty-five aphakic eyes with rhegmatogenous retinal detachment accompanied by PVR were compared with the control group of 156 aphakic eyes with rhegmatogenous retinal detachment without PVR. Unconditional logistic regression analysis identified the following risk factors for developing PVR in order of significance: choroidal detachment (odds ratio 15.41, 95% confidence interval 3.29-72.09), duration of retinal detachment longer than one month (odds ratio 12.07, 95% confidence interval 3.53-41.26), occurrence of retinal detachment within one year following cataract surgery (odds ratio 6.2, 95% confidence interval 1.64-23.47), and history of vitreous loss in cataract surgery (odds ratio 3.91, 95% confidence interval 1.28-11.92).