Multiple sclerosis and related disorders · 2017
Neuromyelitis optica spectrum disorder mimicking multiple sclerosis.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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van Rooij Lucas C, Wattjes Mike P, de Jong Brigit A, van Oosten Bob W
Аннотация
BACKGROUND: MS is a demyelinating CNS disease and has distinct clinical and radiological features. Neuromyelitis optica spectrum disorder (NMOSD) is an antibody related auto-immune disease known for invalidating episodes of myelitis and optic neuritis.
OBJECTIVE: Reporting the case of a 29-year old woman with a disease course typical for relapsing remitting MS with consistent radiological and spinal fluid findings, who developed longitudinally extensive transverse myelitis (LETM) with positive aquaporin 4 antibodies, fulfilling the diagnostic criteria for NMOSD.
METHODS: Case report.
RESULTS: LETM is not consistent with MS. Consider NMOSD even in patients with typical MS and check for aquaporin-4 antibodies, with important treatment consequences.
OBJECTIVE: Reporting the case of a 29-year old woman with a disease course typical for relapsing remitting MS with consistent radiological and spinal fluid findings, who developed longitudinally extensive transverse myelitis (LETM) with positive aquaporin 4 antibodies, fulfilling the diagnostic criteria for NMOSD.
METHODS: Case report.
RESULTS: LETM is not consistent with MS. Consider NMOSD even in patients with typical MS and check for aquaporin-4 antibodies, with important treatment consequences.