Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics · 2007
Long-term intraocular pressure fluctuation and visual field progression in glaucoma patients with low intraocular pressure after post-trabeculectomy phacoemulsification.
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Hong Samin, Kim Chan Yun, Seong Gong Je
Аннотация
BACKGROUND: The aim of this study was to evaluate the association of long-term intraocular pressure (IOP) fluctuation and visual field progression in glaucoma patients with low IOP after post-trabeculectomy phacoemulsification.
METHODS: A total of 688 eyes with primary open-angle glaucoma (POAG) and chronic primary angle-closure glaucoma (CPACG) were included in this study. The patients always had an IOP below 18 mmHg after post-trabeculectomy phacoemulsification. Visual field testing using the standard automated perimetry was periodically performed at 3 months and for at least 3 years postoperatively. The mean deviation on visual field was compared according to the standard deviation (SD) of the postoperative IOP (SD < or = 2 mmHg group vs. SD > 2 mmHg group).
RESULTS: Preoperative and postoperative IOPs during the follow-up period did not differ significantly between the two study groups. Even though the mean deviations on visual field at postoperative 3 months were not different between the two groups, the mean deviations at the last follow-up were significantly worse in the postoperative IOP SD > 2 mmHg group than the postoperative IOP SD < or = 2 mmHg group.
CONCLUSIONS: Less postoperative IOP fluctuation was statistically associated with a slower progression of visual field damage in POAG and CPACG patients who kept low IOPs after the post-trabeculectomy phacoemulsification.
METHODS: A total of 688 eyes with primary open-angle glaucoma (POAG) and chronic primary angle-closure glaucoma (CPACG) were included in this study. The patients always had an IOP below 18 mmHg after post-trabeculectomy phacoemulsification. Visual field testing using the standard automated perimetry was periodically performed at 3 months and for at least 3 years postoperatively. The mean deviation on visual field was compared according to the standard deviation (SD) of the postoperative IOP (SD < or = 2 mmHg group vs. SD > 2 mmHg group).
RESULTS: Preoperative and postoperative IOPs during the follow-up period did not differ significantly between the two study groups. Even though the mean deviations on visual field at postoperative 3 months were not different between the two groups, the mean deviations at the last follow-up were significantly worse in the postoperative IOP SD > 2 mmHg group than the postoperative IOP SD < or = 2 mmHg group.
CONCLUSIONS: Less postoperative IOP fluctuation was statistically associated with a slower progression of visual field damage in POAG and CPACG patients who kept low IOPs after the post-trabeculectomy phacoemulsification.