Srpski arhiv za celokupno lekarstvo · 2014
[Efficacy and safety of balloon valvuloplasty as a treatment of choice for pulmonary stenosis in children and adolescents].
Клиническое исследованиеСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Аннотация
INTRODUCTION: Pulmonary artery stenosis (PS) is a congenital heart defect which occurs in 10% of all congenital heart defects. Pulmonary balloon valvuloplasty (BVP) has been the treatment of choice of PS over the last 30 years.
OBJECTIVE: The purpose of this study was to evaluate the effi- cacy of this method based on middle-term hospital follow-up, and safety of BVP based on our experience.
METHODS: The study included 88 patients diagnosed with PS.The patients were divided into three groups based on the severity of the disease. Also, they were divided into two age groups in order to analyze the frequency of complications. Hemodynamic measurements and echocardiography results were recorded before, 24-36 hours after BVP and at the end of follow-up.
RESULTS: The studied group involved patients of average age 3.75 ± 4.3 years (20 days to 17 years). Immediately after BVP a significant decrease of pressure gradient across the pulmonary valve (PV) was recorded in all patients; this result was similar in all 3 groups of patients regardless of the severity of stenosis (p < 0.001). Complications of BVP occurred most commonly in children up to 12 months of age (ventricular tachycardia 4.5% and supraventricular tachycardia 6.8%). Pulmonary valve in- sufficiency after dilatation occurred in 6.6% of cases, and was most common in children aged up to 12 months. In 87 (98.9%) patients BVP was a definitive solution, and a significant residual stenosis was not recorded during follow-up.
CONCLUSION: BVP is a safe and effective procedure in the treatment of isolated PS in children, regardless of the severity of stenosis but also regardless of patients' age.
OBJECTIVE: The purpose of this study was to evaluate the effi- cacy of this method based on middle-term hospital follow-up, and safety of BVP based on our experience.
METHODS: The study included 88 patients diagnosed with PS.The patients were divided into three groups based on the severity of the disease. Also, they were divided into two age groups in order to analyze the frequency of complications. Hemodynamic measurements and echocardiography results were recorded before, 24-36 hours after BVP and at the end of follow-up.
RESULTS: The studied group involved patients of average age 3.75 ± 4.3 years (20 days to 17 years). Immediately after BVP a significant decrease of pressure gradient across the pulmonary valve (PV) was recorded in all patients; this result was similar in all 3 groups of patients regardless of the severity of stenosis (p < 0.001). Complications of BVP occurred most commonly in children up to 12 months of age (ventricular tachycardia 4.5% and supraventricular tachycardia 6.8%). Pulmonary valve in- sufficiency after dilatation occurred in 6.6% of cases, and was most common in children aged up to 12 months. In 87 (98.9%) patients BVP was a definitive solution, and a significant residual stenosis was not recorded during follow-up.
CONCLUSION: BVP is a safe and effective procedure in the treatment of isolated PS in children, regardless of the severity of stenosis but also regardless of patients' age.