[Body roundness index as a predictor of metabolic syndrome in patients with obesity and type 2 diabetes mellitus].

Background: the body roundness index (BRI) has recently been proposed as a potential marker of obesity. The objective was to evaluate the relationship between BRI and metabolic syndrome (MS) in Caucasian patients with obesity and type 2 diabetes mellitus. Methods: adiposity parameters, blood pressure, fasting glucose, insulin concentration, insulin resistance (HOMA-IR), lipid profile, C-reactive protein, adipokines, and the prevalence of MS were evaluated in 358 patients. Results: among the participants, 258 (72.1 %) were diagnosed with MS. The risk of developing MS in the high BRI group was OR: 3.61 (95 % CI: 2.15-6.07; p = 0.02). The area under the curve (AUC) for HOMA-IR to detect MS was 0.67 (0.59-0.78; p = 0.01), with a cut-off value of 3.37 based on the Youden index (sensitivity 74.9 % and specificity 64.7 %). For BRI, the AUC was 0.78 (0.68-0.85; p = 0.001). The Youden index determined a cut-off value of 10.31 (sensitivity 84.6 % and specificity 72.9 %). Conclusions: BRI demonstrates the ability to correlate with adiposity parameters and biomarkers in patients with type 2 diabetes mellitus and obesity, showing a capacity to detect MS.