Future microbiology · 2021
Role of advanced respiratory support in acute respiratory failure in clinically frail patients with COVID-19.
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Nadeem Iftikhar, Jordon Louise, Rasool Masood Ur, Mahdi Noor, Kumar Ritesh, Rehman Zahra, Tilley Craig J, Kang Simran, Rai Amrita, Lok She, McMillan Alison
Аннотация
Background: The main aim of this study was to assess the efficacy of advanced respiratory support (ARS) for acute respiratory failure in do-not-attempt cardiopulmonary resuscitation order (DNACPR) COVID-19 patients. Methods: In this single-center study, the impact of different types of ARS modality, PaO2/FiO2 (PF) ratio, clinical frailty score (CFS) and 4C score on mortality was evaluated. Results: There was no significant difference in age, type of ARS modality, PF ratio and 4C scores between those who died and those who survived. Overall survival rates/hospital discharge of patients still requiring ARS at 5 and 7 days post admission were 20 and 17%, respectively. Conclusion: Our study showed that ARS can be a useful tool in frail, elderly and high-risk COVID-19 patients irrespective of high 4C mortality score.