Rifabutin-associated uveitis in an immunosuppressed pediatric patient without acquired immunodeficiency syndrome.

PURPOSE: To describe a case of bilateral, symptomatic rifabutin-associated uveitis with hypopyon and vitreal opacities in an immunosuppressed pediatric patient without acquired immunodeficiency syndrome (AIDS).

METHOD: Case report. An 8-year-old boy presented with bilateral uveitis 24 months after a bilateral lung transplant.

RESULTS

Our patient, whose medications included rifabutin, clarithromycin, and immunosuppressive agents, responded to discontinuation of the rifabutin and initiation of intensive topical corticosteroid therapy with complete resolution of the uveitis.

CONCLUSION

Rifabutin-associated uveitis may occur in a non-AIDS pediatric patient.