Application of Anterior Segment Optical Coherence Tomography in Detecting Kayser-Fleischer Rings in Wilson Disease.

PURPOSE: To evaluate the presentation of Kayser-Fleischer (KF) rings in the cornea using anterior segment optical coherence tomography (AS-OCT) in patients with Wilson disease (WD).

METHODS

A retrospective analysis was conducted on the clinical data from 31 patients (62 eyes) who were diagnosed with WD, were positive for KF rings, and who were admitted to our hospital between August 2020 and December 2022. All patients underwent slit-lamp and AS-OCT examinations, with the KF ring width measured on AS-OCT grayscale images.

RESULTS

On AS-OCT, the KF ring appeared as a high-reflective band at the level of Descemet membrane. The color band on AS-OCT displayed the ring in shades of yellow-green, yellow, or orange. The width of the KF ring was measured accurately using AS-OCT.

CONCLUSIONS

AS-OCT, when combined with slit-lamp examination, provides a reliable method for evaluating KF rings in patients with WD. The grayscale measurements obtained via AS-OCT offer precise quantification of the corneal KF ring width.