[Experience with the autovaccinal treatment of chronic carriers of typhoid bacteria].

Considering bacterial carriership as a special form of typhoid infection inducing the allergic transformation of the body with the development of delayed type hypersensitivity and believing that vaccinal therapy might be the most promising method for treating the states of this kind, the authors used autovaccine, introduced by the method of epicutaneous electrophoresis in accordance with Alisov's scheme, for the treatment of chronic carriers of typhoid bacteria. The subsequent prolonged (up to 20 years) observation of the carriers revealed that the release of the infective agents became less intensive and the number of persistent carriers decreased 2.5 times as compared with the control group of carriers treated with antibiotics and roborants. The results of the study of morphological changes occurring in the mucous membrane of the small intestine of the carriers indicated that after complex treatment the inflammatory process decreased and in some carriers disappeared.