Efficacy of Pycnogenol® supplementation in remission phases of Sjögren syndrome.

BACKGROUND

The aim of this study was to evaluate the effects of Pycnogenol® supplementation in otherwise healthy subjects with Sjögren syndrome (SS) in a remission phase, who experienced persisting symptoms impairing their quality of life.

METHODS

The control group receiving only standard treatment was composed of 14 subjects, the supplement group included 16 subjects who used Pycnogenol® supplementation.

RESULTS

ESR and oxidative stress levels were high in all subjects at inclusion; both decreased significantly with supplementation (P<0.05). Pycnogenol® significantly improved the majority of symptoms (dry eyes and mouth dryness), diminishing the need for corticosteroids and other treatments.

CONCLUSIONS

Pycnogenol® supplementation in patients with SS in a remission phase may be effective to control inflammation and reduce symptoms.