The Journal of pediatrics · 2002
Parental history and early-onset type 2 diabetes in African Americans and Latinos in Chicago.
СтатьяПоддержка службы здравоохранения СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Onyemere Kingsley U, Lipton Rebecca B
Аннотация
OBJECTIVE: To examine the role of parental diabetes mellitus (DM) in the development of type 2 DM among children and adolescents from high-risk ethnic groups.
STUDY DESIGN: A population-based dataset of insulin-treated diabetes among African American and Latino children <18 years old yielded 243 cases who completed an interview. A subset with features of type 2 DM was identified (n = 44) using one or more criteria: stopping insulin therapy; using oral hypoglycemic agents; acanthosis nigricans; polycystic ovary syndrome; denoted "atypical" or "type 2" by a physician.
RESULTS: Of all the patients, 76% had no known diabetic parent; 7% had father only; 15% had mother only; and 2.5% had two diabetic parents. Parental DM was more likely in type 2 than in type 1 children (only paternal, 15.9% vs 5.5%, P <.02; only maternal, 38.6% vs 9.5%, P <.01; or both, 6.8% vs 1.5%, P <.01).
CONCLUSION: A positive parental history of DM appears to be more strongly related to childhood type 2 than to type 1 DM. Whether this is a reflection of genetic or behavioral factors is yet unclear.
STUDY DESIGN: A population-based dataset of insulin-treated diabetes among African American and Latino children <18 years old yielded 243 cases who completed an interview. A subset with features of type 2 DM was identified (n = 44) using one or more criteria: stopping insulin therapy; using oral hypoglycemic agents; acanthosis nigricans; polycystic ovary syndrome; denoted "atypical" or "type 2" by a physician.
RESULTS: Of all the patients, 76% had no known diabetic parent; 7% had father only; 15% had mother only; and 2.5% had two diabetic parents. Parental DM was more likely in type 2 than in type 1 children (only paternal, 15.9% vs 5.5%, P <.02; only maternal, 38.6% vs 9.5%, P <.01; or both, 6.8% vs 1.5%, P <.01).
CONCLUSION: A positive parental history of DM appears to be more strongly related to childhood type 2 than to type 1 DM. Whether this is a reflection of genetic or behavioral factors is yet unclear.