Seminars in ophthalmology · 2007
Ethambutol neuroretinopathy.
Клинический случайСтатьяОбзорНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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История · было → стало
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Vistamehr Setareh, Walsh Thomas J, Adelman Ron A
Аннотация
OBJECTIVE: To describe the clinical features of ethambutol neuroretinopathy.
DESIGN: Case report and meta-analysis of the literature.
PARTICIPANTS: A patient with clinical and electrophysiological findings suggestive of ethambutol neuroretinopathy.
TESTING: Electroretinogram, electro-oculogram and visual fields.
MAIN OUTCOME MEASURE: Clinical and electrophysiological findings.
RESULTS: 101 cases were reviewed, retinal findings include retinal pigment epithelial changes, macular edema, flame-shaped hemorrhages. Electroretinogram findings include decreased amplitude and abnormal wave pattern in full field ERG, multifocal or pattern ERG and electro-oculogram findings include abnormal Arden ratio.
CONCLUSIONS: Clinical, electrophysiological and in vitro studies support the toxic effect of ethambutol on the retina. Therefore ethambutol ocular toxicity may be a neuroretinopathy.
DESIGN: Case report and meta-analysis of the literature.
PARTICIPANTS: A patient with clinical and electrophysiological findings suggestive of ethambutol neuroretinopathy.
TESTING: Electroretinogram, electro-oculogram and visual fields.
MAIN OUTCOME MEASURE: Clinical and electrophysiological findings.
RESULTS: 101 cases were reviewed, retinal findings include retinal pigment epithelial changes, macular edema, flame-shaped hemorrhages. Electroretinogram findings include decreased amplitude and abnormal wave pattern in full field ERG, multifocal or pattern ERG and electro-oculogram findings include abnormal Arden ratio.
CONCLUSIONS: Clinical, electrophysiological and in vitro studies support the toxic effect of ethambutol on the retina. Therefore ethambutol ocular toxicity may be a neuroretinopathy.