The Safety and Clinical Effects of Amisulpride in Children and Adolescents with Psychiatric Disorders: A Case Series.

Objectives

The objective of this study was to explore the safety and clinical effects of amisulpride in children and adolescents with psychiatric disorders.

Methods

This case series included six patients, aged 11 to 19 years, diagnosed with affective disorder, autism, anxiety, psychosis, and obsessive-compulsive disorder, and treated with amisulpride at doses ranging from 100 to 400 mg per day.

Results

Amisulpride appeared to reduce psychotic and behavioral symptoms. Observed side effects included increased appetite, weight gain, sedation, and mild extrapyramidal symptoms.

Conclusion

Amisulpride may have promise for study and future use in children and adolescents with psychiatric disorders and severe symptoms.