Медицинская библиотека · Influenza and other respiratory viruses · 2024

Late-Season Influenza Vaccine Effectiveness Against Medically Attended Outpatient Illness, United States, December 2022-April 2023.

Chung Jessie R, Shirk Philip, Gaglani Manjusha, Mutnal Manohar B, Nowalk Mary Patricia, Moehling Geffel Krissy, House Stacey L, Curley Tara, Wernli Karen J, Kiniry Erika L, Martin Emily T, Vaughn Ivana A, Murugan Vel, Lim Efrem S, Saade Elie, Faryar Kiran, Williams Olivia L, Walter Emmanuel B, Price Ashley M, Barnes John R, DaSilva Juliana, Kondor Rebecca, Ellington Sascha, Flannery Brendan

СтатьяПоддержка службы здравоохранения СШАПоддержка NIH: внешняя программаПеревод в очереди

Аннотация

BACKGROUND

The 2022-23 US influenza season peaked early in fall 2022.

METHODS

Late-season influenza vaccine effectiveness (VE) against outpatient, laboratory-confirmed influenza was calculated among participants of the US Influenza VE Network using a test-negative design.

RESULTS

Of 2561 participants enrolled from December 12, 2022 to April 30, 2023, 91 laboratory-confirmed influenza cases primarily had A(H1N1)pdm09 (6B.1A.5a.2a.1) or A(H3N2) (3C.2a1b.2a.2b). Overall, VE was 30% (95% confidence interval -9%, 54%); low late-season activity precluded estimation for most subgroups.

CONCLUSIONS

2022-23 late-season outpatient influenza VE was not statistically significant. Genomic characterization may improve the identification of influenza viruses that circulate postinfluenza peak.

Для цитирования: Chung Jessie R, Shirk Philip, Gaglani Manjusha, Mutnal Manohar B, Nowalk Mary Patricia, Moehling Geffel Krissy, House Stacey L, Curley Tara, Wernli Karen J, Kiniry Erika L, Martin Emily T, Vaughn Ivana A, Murugan Vel, Lim Efrem S, Saade Elie, Faryar Kiran, Williams Olivia L, Walter Emmanuel B, Price Ashley M, Barnes John R, DaSilva Juliana, Kondor Rebecca, Ellington Sascha, Flannery Brendan. Late-Season Influenza Vaccine Effectiveness Against Medically Attended Outpatient Illness, United States, December 2022-April 2023.. Influenza and other respiratory viruses. 2024. DOI: 10.1111/irv.13342.

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