[Mucoraceae mycoses: clinical aspects and pathology in ten patients].

Zygomycosis is characterized by a very high lethality, often favoured by rapid fungal growth in blood vessels causing the formation of thrombi and infarcts in several organs, a disease poor in symptoms. A disseminated mycosis normally is a complication of a granulocytopenia which is in our days more frequently observed as localized manifestation, whereas the typical rhinocerebral manifestation complicating diabetic ketoacidosis has become more rare. The diagnosis of zygomycosis can apparently be obtained easier by histology than by culture. The prognosis of zygomycosis can be improved by: 1. an early examination by biopsy, 2. if possible a rapid correction of predisposing factors (e.g. correction of acidosis), 3. an early antimycotic therapy by amphotericin B in risk patients, even if no causative agent can be cultured.