Nature communications · 2023
Virus diversity, wildlife-domestic animal circulation and potential zoonotic viruses of small mammals, pangolins and zoo animals.
СтатьяПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
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Cui Xinyuan, Fan Kewei, Liang Xianghui, Gong Wenjie, Chen Wu, He Biao, Chen Xiaoyuan, Wang Hai, Wang Xiao, Zhang Ping, Lu Xingbang, Chen Rujian, Lin Kaixiong, Liu Jiameng, Zhai Junqiong, Liu Ding Xiang, Shan Fen, Li Yuqi, Chen Rui Ai, Meng Huifang, Li Xiaobing, Mi Shijiang, Jiang Jianfeng, Zhou Niu, Chen Zujin, Zou Jie-Jian, Ge Deyan, Yang Qisen, He Kai, Chen Tengteng, Wu Ya-Jiang, Lu Haoran, Irwin David M, Shen Xuejuan, Hu Yuanjia, Lu Xiaoman, Ding Chan, Guan Yi, Tu Changchun, Shen Yongyi
Аннотация
Wildlife is reservoir of emerging viruses. Here we identified 27 families of mammalian viruses from 1981 wild animals and 194 zoo animals collected from south China between 2015 and 2022, isolated and characterized the pathogenicity of eight viruses. Bats harbor high diversity of coronaviruses, picornaviruses and astroviruses, and a potentially novel genus of Bornaviridae. In addition to the reported SARSr-CoV-2 and HKU4-CoV-like viruses, picornavirus and respiroviruses also likely circulate between bats and pangolins. Pikas harbor a new clade of Embecovirus and a new genus of arenaviruses. Further, the potential cross-species transmission of RNA viruses (paramyxovirus and astrovirus) and DNA viruses (pseudorabies virus, porcine circovirus 2, porcine circovirus 3 and parvovirus) between wildlife and domestic animals was identified, complicating wildlife protection and the prevention and control of these diseases in domestic animals. This study provides a nuanced view of the frequency of host-jumping events, as well as assessments of zoonotic risk.