[Therapeutic application of vitamin D, its derivatives and analogues (author's transl)].

The synthesis of vitamin D derivatives and analogues, more especially that of 25-hydroxyvitamin D, 1, 25-dihydroxyvitamin D et l alpha-hydroxyvitamin D has opened a new field of investigation in pediatric pharmacology. These substances allows to achieve replacement therapy in pathological states characterized by a decreased formation of 25-hydroxyvitamin D (hepato-cellular diseases) or, 1, 25-dihydroxyvitamin D (renal diseases). Moreover, their utilisation at pharmacological doses has improved the therapeutic results in a number of pediatric diseases. In the present report are more especially summarized the results obtained with these three derivatives in patients with secondary hyperparathyroidism, hypo or pseudo-hypoparathyroidism.