Gan to kagaku ryoho. Cancer & chemotherapy · 2013
[A case of carcinoma associated with anal fistula effectively treated with preoperative chemoradiotherapy].
Клинический случайАннотация на английскомСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Nishigaki Takahiko, Murata Kohei, Okubo Hirofumi, Mikami Koji, Okamura Syu, Wada Yuma, Kato Ryo, Makino Shunichiro, Okada Kazuyuki, Fukuchi Nariaki, Ebisui Chikara, Kinuta Masakatsu
Аннотация
A 60-year-old man presented with anal pain. He was diagnosed as having perianal abscess and carcinoma associated with anal fistula. We performed chemoradiotherapy (radiation, total 50.4 Gy; capecitabine 2,000 mg/m2) followed by chemotherapy( XELOX, 2 courses: capecitabine 2,000 mg/m2, oxaliplatin 130 mg/m2). After chemoradiotherapy, the tumor significantly reduced in size. Laparoscopic abdominoperineal resection of the rectum, extended resection of the perianal region, and reconstruction of the perianal skin defect using a rectus abdominis musculocutaneous flap were performed. Histopathologically, the tumor was classified as tub2, pMP, ly0, v0, pN0 (0/3), pStage I, and the therapeutic efficacy was classified as Grade 2. Chemoradiation appears to be effective for the treatment of carcinomas associated with anal fistula.