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Journal of the American Academy of Dermatology · 2022

Dermatoscopic and clinical features of congenital or congenital-type nail matrix nevi: A multicenter prospective cohort study by the International Dermoscopy Society.

СтатьяМногоцентровое исследованиеПоддержка исследования: вне правительства СШАНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
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Pham Félix, Boespflug Amélie, Duru Gérard, Phan Alice, Poulalhon Nicolas, Weiler Laura, Tanaka Masaru, Lallas Aimilios, Ogata Dai, Davaine Anne Céline, Bahadoran Philippe, Balguerie Xavier, Kamińska-Winciorek Grażyna, Tromme Isabelle, Correia Osvaldo, Kim Moon-Bum, Marghoob Ashfaq A, Linda Martin, Guitera Pascale, Meziane Mariame, Miquel Juliette, Mun Je-Ho, Argenziano Giuseppe, Bessis Didier, Bourke Johnny, Mijuskovic Zeljko, Chiaverini Christine, Corven-Benoit Cloé, Droitcourt Catherine, Skowron François, Marque Myriam, Zalaudek Iris, Rosendahl Cliff, Moreno-Ramirez David, Vabres Pierre, Haenssle Holger, Malvehy Josep, Puig Susana, Robert Caroline, Schopf Thomas R, Scope Alon, Dalle Stéphane, Thomas Luc

Аннотация

BACKGROUND: Congenital nail matrix nevi (NMN) are difficult to diagnose because they feature clinical characteristics suggestive of adult subungual melanoma. Nail matrix biopsy is difficult to perform, especially in children.

OBJECTIVE: To describe the initial clinical and dermatoscopic features of NMN appearing at birth (congenital) or after birth but before the age of 5 years (congenital-type).

METHODS: We conducted a prospective, international, and consecutive data collection in 102 hospitals or private medical offices across 30 countries from 2009 to 2019.

RESULTS: There were 69 congenital and 161 congenital-type NMNs. Congenital and congenital-type NMN predominantly displayed an irregular pattern of longitudinal microlines (n = 146, 64%), reminiscent of subungual melanoma in adults. The distal fibrillar ("brush-like") pattern, present in 63 patients (27.8%), was more frequently encountered in congenital NMN than in congenital-type NMN (P = .012). Moreover, congenital NMN more frequently displayed a periungual pigmentation (P = .029) and Hutchinson's sign (P = .027) than did congenital-type NMN.

LIMITATIONS: Lack of systematic biopsy-proven diagnosis and heterogeneity of clinical and dermatoscopic photographs.

CONCLUSION: Congenital and congenital-type NMN showed worrisome clinical and dermatoscopic features similar to those observed in adulthood subungual melanoma. The distal fibrillar ("brush-like") pattern is a suggestive feature of congenital and congenital-type NMN.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты