Idiopathic thrombocytopenic purpura in children.

Idiopathic thrombocytopenic purpura is a disorder characterized by antibody-mediated platelet destruction. Other than thrombocytopenia and its consequences, the physical and laboratory examination of the child with ITP is normal. The prognosis in children is excellent; 90 percent will recover spontaneously within one year. Serious hemorrhage is uncommon and conservative management is appropriate. Aspirin and potential trauma should be avoided. Transfusions are rarely necessary or helpful. Corticosteroids may cause a more rapid rise in the platelet count but do not influence the long-term prognosis.