Annals of epidemiology · 2025
Rising maternal obesity and persistent suboptimal gestational weight gain among women living with HIV in Kenya: A retrospective cohort study 2008-2017.
СтатьяНазвание и аннотация: Перевод пока не подготовлен
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Diwan Nazha M, Mbithe Betty, Kinuthia John, Cagle Tony J, Kibaara Charles, Adly Andrew Nagy, Chung Michael H, Bengtson Angela M
Аннотация
PURPOSE: To describe trends in pre-pregnancy BMI (ppBMI), gestational weight gain (GWG), and associations with birth outcomes among women living with HIV (WLWH) in Kenya.
METHODS: WLWH who initiated antenatal care ≤ 14 weeks of gestation at the Coptic Hope Center in Nairobi and Maseno, Kenya between 2008 and 2017 were identified. PpBMI was defined using first-trimester BMI (Kg/m2); GWG was assessed using weekly GWG rate in the second-and-third trimesters per National Academy of Medicine (NAM) guidelines. Associations between GWG z-scores and birthweight, low/high birthweight, and emergency cesarean-section (c-section) were examined using mixed-effects models.
RESULTS: We identified 1190 pregnancies, of which more than half had overweight (34.3 %) or obese (18.0 %) ppBMI, 45.1 % had normal ppBMI, and 2.6 % were underweight. From 2008-2017, obese ppBMI among WLWH doubled, while normal ppBMI decreased by 8.2 %. Suboptimal GWG rates, both above and below NAM-recommendations, were common across ppBMI categories. A one-unit increase in GWG z-score was associated with higher birthweight (+45.96, 95 % CI: 15.29-75.17) and increased risk of emergency c-section (aRR=1.35, 95 % CI: 1.03-1.82).
CONCLUSION: From 2008-2017, maternal obesity among WLWH in Kenya increased, while GWG rates remained suboptimal. Future studies should examine barriers and possible interventions to address rising ppBMI and promote healthy GWG among WLWH.
METHODS: WLWH who initiated antenatal care ≤ 14 weeks of gestation at the Coptic Hope Center in Nairobi and Maseno, Kenya between 2008 and 2017 were identified. PpBMI was defined using first-trimester BMI (Kg/m2); GWG was assessed using weekly GWG rate in the second-and-third trimesters per National Academy of Medicine (NAM) guidelines. Associations between GWG z-scores and birthweight, low/high birthweight, and emergency cesarean-section (c-section) were examined using mixed-effects models.
RESULTS: We identified 1190 pregnancies, of which more than half had overweight (34.3 %) or obese (18.0 %) ppBMI, 45.1 % had normal ppBMI, and 2.6 % were underweight. From 2008-2017, obese ppBMI among WLWH doubled, while normal ppBMI decreased by 8.2 %. Suboptimal GWG rates, both above and below NAM-recommendations, were common across ppBMI categories. A one-unit increase in GWG z-score was associated with higher birthweight (+45.96, 95 % CI: 15.29-75.17) and increased risk of emergency c-section (aRR=1.35, 95 % CI: 1.03-1.82).
CONCLUSION: From 2008-2017, maternal obesity among WLWH in Kenya increased, while GWG rates remained suboptimal. Future studies should examine barriers and possible interventions to address rising ppBMI and promote healthy GWG among WLWH.