A study to compare the effect of adding 12 days DEC regimen to 6 years annual mass drug administration to eliminate microfilaraemia infection in the community in rural Kanpur, Uttar Pradesh, India.

Lymphatic filariasis is a major public health problem of tropical countries. Although its elimination is planned as global effort using mass drug administration in affected communities but its impact has been influenced by MDA coverage across countries. The drug coverage is affected by fever as side effect and its continuation for over 6 years which affect the population participation. Therefore alternative approaches are needed which can show impact faster than standard MDA. Present research using additional 12 days dose of DEC to mf carriers, show that if drug coverage could be regular, sustainable impact could be created in 4 years.