[The secretory activity of the stomach, duodenum and pancreas in patients with chronic opisthorchiasis].

Serum IgE, gastrin, and insulin levels were measured by radioimmunoassay and gastric secretion was studied by the method of submaximal histamine stimulation in 59 inhabitants of Sverdlovsk and 51 former inhabitants of Tyumen Province, who had chronic opisthorchiasis. In the hypoendemic focus, increased IgE content was observed mostly in young people, and in the hyperendemic focus it was in middle-aged and old people, this parameter correlating with decreased levels of gastrin and insulin in the serum. Gastric basal acid secretion was decreased in more than 70% patients from the both groups. However, hyperimmunoglobulinemia tends to show elevated hydrochloric acid debit.