Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2015
The Emergence of Zoonotic Onchocerca lupi Infection in the United States--A Case-Series.
Клинический случайСтатьяНазвание и аннотация: Перевод пока не подготовлен
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Cantey Paul T, Weeks Jessica, Edwards Morven, Rao Suchitra, Ostovar G Amin, Dehority Walter, Alzona Maria, Swoboda Sara, Christiaens Brooke, Ballan Wassim, Hartley John, Terranella Andrew, Weatherhead Jill, Dunn James J, Marx Douglas P, Hicks M John, Rauch Ronald A, Smith Christiana, Dishop Megan K, Handler Michael H, Dudley Roy W R, Chundu Kote, Hobohm Dan, Feiz-Erfan Iman, Hakes Joseph, Berry Ryan S, Stepensaski Shelly, Greenfield Benjamin, Shroeder Laura, Bishop Henry, de Almeida Marcos, Mathison Blaine, Eberhard Mark
Аннотация
This case-series describes the 6 human infections with Onchocerca lupi, a parasite known to infect cats and dogs, that have been identified in the United States since 2013. Unlike cases reported outside the country, the American patients have not had subconjunctival nodules but have manifested more invasive disease (eg, spinal, orbital, and subdermal nodules). Diagnosis remains challenging in the absence of a serologic test. Treatment should be guided by what is done for Onchocerca volvulus as there are no data for O. lupi. Available evidence suggests that there may be transmission in southwestern United States, but the risk of transmission to humans is not known. Research is needed to better define the burden of disease in the United States and develop appropriately-targeted prevention strategies.